suggested use of this reagent is 0.5 µg per 106 cells in 100 µl
It is recommended that the reagent be titrated for optimal performance for
GM1CD3 reacts with CD3, a 20-26 kDa
molecule, which is expressed on all mature T lymphocytes (approximately
60-80% of normal human peripheral blood lymphocytes), NK-T cells and
some thymocytes. CD3 associated with the T-cell receptor a/b or g/d
dimer also plays a role in T-cell activation and signal transduction
during antigen recognition.
* CD3 mAb is used to count mature T cells in blood.