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Mouse anti-Human CD25, FITC Conjugated mAb.
[GMH0251F]
Product Details

Catalog No./Size: GMH0251F-025/25 Tests
GMH0251F-100/100 Tests
Vol.per.Test: 10 μl/Test
Clone: GM1CD25
Isotype: Mouse IgG2a
Reactivity: Human,Not yet tested in other species.
Workshop: N/A
Storage Buffer: Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide and 0.2% (w/v) BSA
Storage Condition: Store at 4C.DO NOT FREEZE. LIGHT SENSITIVE MATERIAL.
Applications: Flow Cytometry
Applications Notes:

FACS: Use 10µl for 106 cells

Description:

GM1CD25 reacts with CD25 antigen, a chain of low-affinity interleukin-2 receptor ( IL-2Ra ), which is expressed on activated cells including T, B, NK cells and monocytes. The antigen also prsent on subset of thymocytes, HTLV-1 transformed T cell lines, EBV transformed B cells, myeloid precursors and oligodendrocytes. The high affinity IL-2 receptor is formed by the noncovalent association of of a ( 55 kDa, CD25 ), b ( 75 kDa , CD122 ), and g subunit ( 70 kDa, CD132 ). The interaction of IL-2 with IL-2R induces the activation and proliferation of T, B , NK cells and macrophages. CD4+/CD25+ cells might directly regulate the function of responsive T cells.

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