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Mouse anti-Human CD22, FITC Conjugated mAb.
[GMH0222F]
Product Details

Catalog No./Size: GMH0222F-025/25 Tests
GMH0222F-100/100 Tests
Vol.per.Test: 10 μl/Test
Clone: GM1CD22
Isotype: Mouse IgG1
Reactivity: Human,Not yet tested in other species.
Workshop: N/A
Storage Buffer: Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide and 0.2% (w/v) BSA
Storage Condition: Store at 4C.DO NOT FREEZE. LIGHT SENSITIVE MATERIAL.
Applications: Flow Cytometry
Applications Notes:

FACS: Use 10µl for 106 cells

Description:

GM1CD22 reacts with CD22, a 140 kDa B-cell specific molecule, expressed in the cytoplasm of all B lymphocytes and on the cell surface of only mature B cells. CD22 antigen is present in the most B-cell leukemias and lymphomas but not T-cell leukemias. In contrast with CD10, CD19 and CD20 antigen, CD22 antigen is still present on lymphoplasmacytoid cells but is dininished on the fully mature plasma cells. CD22 is an adhesion molecule and plays a role in B cell activation as a signaling molecule.
*CD22 antibody has been used to treat leukemia and lymphoma.

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