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Mouse anti-Human CD22,Purified mAb.
[GMH0222Z]
Product Details

Catalog No./Size: GMH0222Z-025/25 ug
GMH0222Z-100/100 ug
Clone: GM1CD22
Isotype: Mouse IgG1
Reactivity: Human,Not yet tested in other species.
Workshop: N/A
Storage Buffer: Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide
Storage Condition: Store at 4C.
Applications: Flow Cytometry
Applications Notes:

FACS: The suggested use of this reagent is 0.5 µg per 106 cells in 100 µl volume.
It is recommended that the reagent be titrated for optimal performance for each application.

Description:

GM1CD22 reacts with CD22, a 140 kDa B-cell specific molecule, expressed in the cytoplasm of all B lymphocytes and on the cell surface of only mature B cells. CD22 antigen is present in the most B-cell leukemias and lymphomas but not T-cell leukemias. In contrast with CD10, CD19 and CD20 antigen, CD22 antigen is still present on lymphoplasmacytoid cells but is dininished on the fully mature plasma cells. CD22 is an adhesion molecule and plays a role in B cell activation as a signaling molecule.
*CD22 antibody has been used to treat leukemia and lymphoma.

For more information, please visit this products Datasheet.
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