FACS: Use 10µl for 106
CB16 reacts with
human CD16, a 50-65 kDa Fcg receptor IIIa (FcgRIII), expressed on NK
cells, monocytes/macrophages and granulocytes. It is a human NK cell
associated antigen. CD16 is a low affinity receptor for IgG which
functions in phagocytosis and ADCC, as well as in signal transduction
and NK cell activation. The CD16 antibody blocks the binding of soluble
immune complexes to granulocytes.
This clone is cross reactive with non-human primate.