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Mouse anti-Human CD14,Purified mAb.
[GMH0142Z]
Product Details

Catalog No./Size: GMH0142Z-025/25 ug
GMH0142Z-100/100 ug
Clone: GM2CD14
Isotype: Mouse IgG1
Reactivity: Human,Not yet tested in other species.
Workshop: N/A
Storage Buffer: Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide
Storage Condition: Store at 4C.
Applications: Flow Cytometry
Applications Notes:

FACS: The suggested use of this reagent is 0.06 µg per 106 cells in 100 µl volume.
It is recommended that the reagent be titrated for optimal performance for each application.

Description:

GM2CD14 reacts with CD14, a 53-55 kDa molecule. CD14 is a human high affinity cell-surface receptor for complexes of lipopolysaccharide (LPS-endotoxin) and serum LPS-binding protein (LPB). CD14 antigen has a strong presence on the surface of monocytes/macrophages, is weakly expressed on granulocytes, but not expressed by myeloid progenitor cells. CD14 functions as a receptor for endotoxin; when the monocytes become activated they release cytokines such as TNF, and up-regulate cell surface molecules including adhesion molecules.This clone is cross reactive with non-human primate.

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