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Mouse anti-Human CD11b,Purified mAb.
[GMH0115Z]
Product Details

Catalog No./Size: GMH0115Z-025/25 ug
GMH0115Z-100/100 ug
Clone: GM2CD11
Isotype: Mouse IgG1
Reactivity: Human,Not yet tested in other species.
Workshop: N/A
Storage Buffer: Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide
Storage Condition: Store at 4C.
Applications: Flow Cytometry
Applications Notes:

FACS: The suggested use of this reagent is 0.25 µg per 106 cells in 100 µl volume.
It is recommended that the reagent be titrated for optimal performance for each application.

Description:

GM2CD11 reacts with CD11b, a member of the integrin a chain family with 165 kDa MW. which is expressed on NK cells, monocytes, granulocytes and subsets of T and B cells. It associates with CD18 to form CD11b/CD18 complex .The cellular function of CD11b is on neutrophil and monocyte interactions with stimulated endothelium; Phagocytosis of iC3b or IgG coated particles as a receptor; Chemotaxis and apoptosis.
* CD11b is absent in Leukocyte Adhesion Deficiency (LAD-1) patients who have major problems with bacterial infections.
This clone is cross reactive with non-human primate.

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