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Mouse anti-Human CD11a, PE Conjugated mAb.
[GMH011P]
Product Details

Catalog No./Size: GMH011P-025/25 Tests
GMH011P-100/100 Tests
Vol.per.Test: 10 μl/Test
Clone: TS1/22.1.1.13
Isotype: Mouse IgG1
Reactivity: Human,Not yet tested in other species.
Workshop: N/A
Storage Buffer: Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide and 0.2% (w/v) BSA
Storage Condition: Store at 4C.DO NOT FREEZE. LIGHT SENSITIVE MATERIAL.
Applications: Flow Cytometry
Applications Notes:

FACS: Use 10µl for 106 cells

Normal human peripheral blood lymphocytes analyzed with PE CD11a(TS1/22.1.1.13) mAb.

Description:

TS1/22.1.1.13 reacts with CD11a, a 180 kDa molecule. CD11a is the a chain of the leukocyte function associated antigen-1 (LFA-1a), and is expressed on all leukocytes including T and B cells, monocytes, and granulocytes, but is absent on non-hematopoietic tissue and human platelets. CD11/CD18 (LFA-1), a member of the integrin subfamily, is a leukocyte adhesion receptor that is essential for cell-to-cell contact, such as lymphocyte adhesion, NK and T-cell cytolysis, and T-cell proliferation. CD11/CD18 is also involved in the interaction of leucocytes with endothelium.
*CD11a antibody has been used to reduces graft failure for bone marrow grafts in immunodeficient children.
This clone is cross reactive with non-human primate.

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