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Mouse anti-Human CD11a,Purified mAb.
[GMH011Z]
Product Details

Catalog No./Size: GMH011Z-025/25 ug
GMH011Z-100/100 ug
Clone: TS1/22.1.1.13
Isotype: Mouse IgG1
Reactivity: Human,Not yet tested in other species.
Workshop: N/A
Storage Buffer: Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide
Storage Condition: Store at 4C.
Applications: Flow Cytometry
Applications Notes:

FACS: The suggested use of this reagent is 0.25 µg per 106 cells in 100 µl volume.
It is recommended that the reagent be titrated for optimal performance for each application.

Description:

TS1/22.1.1.13 reacts with CD11a, a 180 kDa molecule. CD11a is the a chain of the leukocyte function associated antigen-1 (LFA-1a), and is expressed on all leukocytes including T and B cells, monocytes, and granulocytes, but is absent on non-hematopoietic tissue and human platelets. CD11/CD18 (LFA-1), a member of the integrin subfamily, is a leukocyte adhesion receptor that is essential for cell-to-cell contact, such as lymphocyte adhesion, NK and T-cell cytolysis, and T-cell proliferation. CD11/CD18 is also involved in the interaction of leucocytes with endothelium.
*CD11a antibody has been used to reduces graft failure for bone marrow grafts in immunodeficient children.
This clone is cross reactive with non-human primate.

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